1820: Yellow Fever at Middletown

In compliance with that sense of duty which we owe this community, and which only we consult, and shall ever consult, regardless of the censures and reproaches of any man, or any body of men, we now announce to the public, that the yellow fever in its most unequivocal shape, exists in the village of Middletown, (Conn.) which without any exaggeration of expression, may be pronounced one of the most healthy spots in the United States. Three cases, it will be seen, have happened there since the death of the tide-waiter, Harrison, who caught the disease by sleeping one night on board the brig Sea Island, direct from St. Jago de Cuba; all of which have terminated fatally, and which have been traced to a communication with the above infected vessel; by means of foul clothes.

From The Evening Post (New York, New York), Monday, July 3, 1820.
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